POL Scientific / Bladder / Volume 7 / Issue 3 / DOI: 10.14440/bladder.2020.818
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CASE REPORT

Malakoplakia, a malignant mimic

Cameron James Parkin1* George Acland1 Ban Sulaiman2 Mark Louie Johnsun1,3 Edward Latif1
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1 Department of Urology, Gosford Hospital, Central Coast Local Health District, NSW, Australia
2 Department of Anatomical Pathology, Gosford Hospital, Central Coast Local Health District, NSW, Australia
3 School of Medicine and Public Health, University of Newcastle, NSW, Australia
Bladder 2020 , 7(3), 1–3;
Submitted: 27 June 2020 | Revised: 2 August 2020 | Accepted: 5 August 2020 | Published: 2 September 2020
© 2020 by the Author(s). Licensee POL Scientific, USA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Malakoplakia is a chronic inflammatory condition that affects multiple systems, most commonly the urogenital tract. Its clinical presentation is often non-specific, but is typically characterized by recurrent urinary tract infections and haematuria. We report a rare case of intravesical malakoplakia mimicking an aggressive transitional cell carcinoma both in its clinical presentation and in its macroscopic appearance on cystoscopy in an 82-year patient, the oldest reported case in the literature. Malakoplakia has been described in the literature as a benign disease process presenting typically in younger patients. This case demonstrates its ability to cause obstructive uropathy and affect elderly patients. Thus, this case serves as a reminder to consider malakoplakia as a differential in the evaluation of suspected bladder malignancy in patients of all ages.

Keywords
malakoplakia
obstructive uropathy
transitional cell carcinoma
References

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Bladder, Electronic ISSN: 2327-2120 Print ISSN: TBA, Published by POL Scientific