POL Scientific / Bladder / Volume 12 / Issue 1 / DOI: 10.14440/bladder.2024.0077
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CASE REPORT

An unusual distal tibial metastasis from urothelial carcinoma: A case report

Tran Ngoc An Huynh1* Darren Trinh2 Janan Chandrananth2 James Sewell1,3
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1 Department of Urology, Monash Health, Melbourne, Victoria 3806, Australia
2 Department of Orthopedics, Peninsula Health, Melbourne, Victoria 3199, Australia
3 Department of Medicine, Faculty of Medicine, Nursing and Health Science, Monash University, Melbourne, Victoria 3800, Australia
Bladder 2025 , 12(1), e21200041; https://doi.org/10.14440/bladder.2024.0077
Submitted: 6 December 2024 | Revised: 6 January 2025 | Accepted: 27 February 2025 | Published: 21 March 2025
© 2025 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Background: Bladder cancer (BCa) frequently metastasizes to bones, typically affecting the spine and pelvis. Case presentation: Presented here is a case of rare extensive distal tibia metastasis in an 84-year-old female with invasive high-grade urothelial carcinoma, who suffered from rapidly progressive ankle pain and reduced mobility. Imaging and biopsy confirmed metastatic urothelial carcinoma in the tibia, which was managed with surgical fixation and palliative radiotherapy. Although bone metastases in BCa commonly affect other sites, clinicians should consider atypical locations like the tibia in patients with unexplained bone pain. Conclusion: Early diagnosis and intervention are essential for improving patient outcomes and quality of life.

Keywords
Bladder cancer
Urothelial carcinoma
Bone metastasis
Distal tibia
Funding
None.
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Conflict of interest
The authors declare that they have no conflict of interest.
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Bladder, Electronic ISSN: 2327-2120 Print ISSN: TBA, Published by POL Scientific